Lalancette C, Leduc J.M., Malo J, Fournier E, Saoud J, Faucher SP, et al. (2020). Legionella quinlivanii strain isolated from human: case report and whole genome sequencing analysis. Official Journal of the Association of Medical Microbiology and Infectious Disease. 5(2). 112-114

Abstract

We describe a strain of Legionella quinlivanii isolated from a bronchoalveolar lavage specimen from an 83-year-old patient in the province of Québec. Identification was done using 16S rRNA sequencing. The strain could replicate efficiently in human THP-1 macrophages and maintained a low level of cytotoxicity. Upon analyzing the whole genome sequencing data, the icm/dot secretion system was present, but the strain lacked some effector genes known to express proteins toxic to cells. The pathogenicity of this Legionella species should be investigated further.

Keywords: Legionella quinlivanii; Bronchoalveolar lavage; Cytotoxicity; Whole genome sequencing.

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